Clinical Trials

Inclusion Criteria:

- Ability to sign informed consent form.

- Body mass index (BMI), 22-29 kg/m^2.

- Diagnosis of Atopic Dermatitis treated with dupilumab for longer than 6 months.

- Diagnosis of Atopic Dermatitis treated with topical steroids or phototherapy.

Exclusion Criteria:

- Any prescription for systemic glucocorticoid, immunosuppressant, antidiabetic
medications in the past 6 months.

- Evidence of diabetes mellitus.

- Morning Cortisol < 5 mg/dl (collected before 10.30 am).

- Presence of acute illness.

- Low hemoglobin or hematocrit.

- Current participation in a weight-loss regimen, with a weight loss > 10% total body
weight in the last 6 months).

- Smoking history in the last 6 months (tobacco, nicotine-containing products including
e-cigarettes).

- Pregnant or breastfeeding.

- Personal history of gastric bypass surgery.

- Previous participation in a clinical trial with an investigational product in the past
30 days, or 5 half-lives, or twice the duration of the biological effect of the
investigational drug (whichever is longest).

- Exposed to more than 4 new chemical entities within 12 months before study enrollment.

- Any other condition or event considered exclusionary by the PI and the study
physician.

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 11/10/22. Questions regarding updates should be directed to the study team contact.