A Study to Compare Two Methods for Following Patients with Pancreatic Cysts

Overview

About this study

The purpose of this study is to compare the two approaches for monitoring pancreatic cysts - more frequent monitoring vs. less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Between 50 and 75 years of age, inclusive.
  • Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status 0-1.
  • Patient must not have acute pancreatitis or a history of chronic pancreatitis.
  • Patient must have received a computed tomography (CT) or magnetic resonance imaging (MRI) within 3 months of registration that revealed a newly identified ≥ 1 cm pancreatic cyst.
  • Women of childbearing potential must not be known to be pregnant.
  • Patient must not have a prior diagnosis of pancreatic cyst or pancreatic malignancy of any type.
  • Patient must not have a history of pancreatic resection.
  • Patient must not have other asymptomatic pancreatic cystic lesion with zero/low malignancy potential (pancreatic pseudocyst, classic serous cystic lesion) on index CT or MRI.
  • Patient must not have a family history of pancreatic adenocarcinoma in 1 or more first degree relatives.
  • Patient must not have pancreatic cyst morphology that would prompt immediate surgical consideration (enhancing mural nodule, solid component in cyst, pancreatic duct > 10 mm, cyst causing obstructive jaundice).
  • Patient must not have a comorbid illness that precludes pancreatic cyst resection.
  • Patient must not be participating in an already established surveillance program.

Exclusion Criteria:

  • Under 50 or over 75 years of age.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Shounak Majumder, M.D.

Contact us for the latest status

Contact information:

Cancer Center Clinical Trials Referral Office

855-776-0015

Jacksonville, Fla.

Mayo Clinic principal investigator

Yan Bi, M.D., Ph.D.

Contact us for the latest status

Contact information:

Cancer Center Clinical Trials Referral Office

855-776-0015

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Rahul Pannala, M.D.

Contact us for the latest status

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

More information

Publications

Publications are currently not available
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CLS-20506534

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