Cardio-Pulmonary Bypass Versus Extracorporeal Membrane Oxygenation as an Independent Risk Factor for Development of Primary Graft Dysfunction Post Lung Transplant

Overview

About this study

The purpose of this study is to to determine if Cardiopulmonary Bypass (CPB) is an independent risk factor for development of Primary Graft Dysfunction (PGD) as compared to Extracorporeal Membrane Oxygenation (ECMO) even when adjusted for all other recipient, donor, biologic and operative risk factors.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age ≥ 18 years old.
On ECMO prior to lung transplant.
Listed for Lung Transplant.
Lung Transplant recipient.
Not pregnant.
Getting either Extracorporeal membrane oxygenation or cardiopulmonary bypass intra-operative at the time of transplant.
Willing to participate in the study.
All data points available for the study for retrospective data.
Getting organs which have undergone ExVIVO Lung Perfusion.

Exclusion Criteria:

Not candidate for Extracoporeal Membrane oxygenation or cardiopulmonary bypass at time of transplant.

Eligibility last updated 8/20/21. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Jacksonville, Fla. Mayo Clinic principal investigator Sadia Shah, M.D.	Open for enrollment	Contact information: Angela Casini MFA (904) 953-3172 Casini.Angela@mayo.edu

Mayo Clinic Location

Status

Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Sadia Shah, M.D.

Open for enrollment

Contact information:

Angela Casini MFA

(904) 953-3172

Casini.Angela@mayo.edu

More information

Publications

Publications are currently not available

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