Outcomes of Positive Pressure Therapy for Obstructive Sleep Apnea Following Endoscopic Sinus Surgery

Overview

About this study

The purpose of this study is to:

Evaluate if there are detrimental effects of restarting CPAP therapy on POD #0-1 in patients undergoing ESS compared to normal controls undergoing ESS without OSA.
Determine if there a difference in perception of pain and post-operative analgesia requirement in OSA patients restarting CPAP on POD #0-1 compared to non-OSA patients.
Determine if there are predictive factors for OSA patients undergoing ESS who require an overnight hospitalization after surgery.
Validate the nocturnal Rhinoconjuctivitis Quality of Life (nRQLQ) questionnaire in the CRS population.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Adult patients who are undergoing bilateral ESS for CRS
Intervention group: pre-existing diagnosis of OSA on positive pressure therapy
Control group: non-OSA patients undergoing ESS

Exclusion Criteria:

Skull base defect
Connective tissue disease such as granulomatosis with polyangiitis or other vasculitis
Bleeding disorder
Odontogenic sinusitis
Draf III frontal sinusotomy
Baseline opioid use
Do not need to exclude if opioids were used briefly for previous surgery, injury, etc.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Janalee Stokken, M.D.	Closed-enrolling by invitation What is this? (?) "Close" Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.	Contact information: Nicole Tombers R.N. (507) 538-1392 Tombers.Nicole@mayo.edu
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Michael Marino, M.D.	Closed-enrolling by invitation What is this? (?) "Close" Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.	Contact information: Devyani Lal M.D. Lal.Devyani@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Janalee Stokken, M.D.

Closed-enrolling by invitation

Contact information:

Nicole Tombers R.N.

(507) 538-1392

Tombers.Nicole@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Michael Marino, M.D.

Closed-enrolling by invitation

Contact information:

Devyani Lal M.D.

Lal.Devyani@mayo.edu

More information

Publications

Publications are currently not available

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