Find trials
Search tips

Autopsy in Neurodegenerative Diseases

Overview

About this study

The purpose of this study is to identify biomarkers from patients with different neurodegenerative diseases including progressive supranuclear palsy, progressive apraxia of speech, primary progressive aphasia, semantic dementia, corticobasal syndrome, posterior cortical atrophy and others. These patients have a clinical diagnosis rendered for research but the underlying pathology is unknown.  

Brain autopsies will be performed in patients who have, or will be enrolled in any of NIH or foundation funded grants. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients with different neurodegenerative diseases including, progressive supranuclear palsy, progressive apraxia of speech, primary progressive aphasia, semantic dementia, corticobasal syndrome, posterior cortical atrophy and others. 
  • Patients who have, or will be enrolled in any of our NIH or foundation funded grants.
  • Patients and families willing to receive information about brain donation.
  • If the patient or family express interest in having an autopsy, they will be mailed or given a packet of information including the Permission for Research Postmortem Brain Examination, HIPAA Consent form, Brain Donation Information sheet, Frequently Asked Questions sheet, as well a Patient Questionnaire.
  • Willing and able to sign a Permission for Research Postmortem Brain Examination form.

Exclusion Criteria:

  • Individuals under 18 years of age.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Keith Josephs, M.D.

Closed-enrolling by invitation

What is this? (?)
"Close"
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Sarah Boland CCRP

(507) 284-3863

Boland.Sarah@mayo.edu

More information

Publications

Publications are currently not available

More about research at Mayo Clinic

.
CLS-20493185

Mayo Clinic Footer