Direct Brain Recording and Stimulation for Memory

Overview

About this study

The primary objectives of this study are (1) to identify biomarkers of successfulmemory encoding and retrieval, and (2) to identify brain regions that can bestimulated to enhance memory performance. The secondary objective is to identifybiomarkers that can be used to predict cognitive impairment following resectionsurgery.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

1. Expected to undergo intracranial electroencephalographic monitoring aspart of a standard clinical procedure for the treatment of pharmacologically resistant epilepsy

2. Age 18 – 65

Exclusion Criteria:

1. Patients who have cognitive impairments that would limit their ability toparticipate in the memory testing

2. Any physical disability that would limit their ability to perform cognitive taskswithin normal limits.

3. Any psychiatric condition that would limit their ability to provide informedconsent or to perform cognitive tasks within normal limits.

4. Any medical condition that would, in the investigator’s opinion, limit thesubject’s participation in the study.

5. Women who are pregnant.

6. Unable or unwilling to provide informed consent

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Gregory Worrell, M.D., Ph.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Gregory Worrell, M.D., Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials