Find trials
Search tips

A Study to Evaluate Screening Contrast Enhanced Digital Mammogram (CEDM) in Study Participants at Intermediate Breast Cancer Risk and Polygenic Risk Score (PRS) Results

Overview

About this study

The purpose of this study is to evaluate a low-cost Contrast Enhanced Digital Mammogram (CEDM) protocol as a supplemental screening method to standard mammographic screening in women at intermediate lifetime-risk (and not undergoing annual MR surveillance) for breast cancer.

 

 

 

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Women aged 35 and older.
  • Have had a negative routine mammogram within the last 12 months.
  • Meets criteria for  intermediate breast cancer risk based on PRS score.

Exclusion Criteria:

  • Known breast cancer at time of study or within 12 months of enrollment.
  • Pregnant or lactating.
  • Contraindication to intravenous iodinated contrast.
  • Unable to understand or sign informed consent.
  • Self-reported signs or symptoms of breast cancer.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Sandhya Pruthi, M.D.

Open for enrollment

Contact information:

Department of Medicine - Clinical Trials Unit

(507) 266-1944

RSTDOMCTU@mayo.edu

More information

Publications

Publications are currently not available

More about research at Mayo Clinic

.
CLS-20491221

Mayo Clinic Footer