Clinical Trials

Inclusion Criteria:

• Provision of signed and dated informed consent form.
• Stated willingness to comply with all study procedures and availability for the duration of the study.
• Male or female subjects, aged ≥ 18 years old.
• Must be able to communicate in English:
  • Help of an interpreter, who can be either MCF interpreter or a family member deemed reasonably proficient and reliable by the LT team.
• Must possess a valid and active email address to receive study questionnaire.
• Access to digital device/s (smartphone, tablet, laptop, desktop) capable of connecting with the internet to allow study participants to complete questionnaires.
• LT candidate listed for LT.
• Caregiver of the LT candidate listed for LT, also agrees to participate in the study.

Exclusion Criteria:

• Liver transplant candidates removed from the LT list.
• Those LT candidates whose primary caregiver will not agree to participate in study.
• Those LT candidates whose caregivers will change after LT (i.e., daughter agrees to care for the patient pre-LT; however, after LT spouse or some other family member assumes caregiving responsibility):
  • In this case, we will use baseline data to assess impact of dyadic coping on LT related outcomes until peri-LT period but will not use the data to assess the primary outcome;
  • These patients will not count toward desired sample size, as sample size calculation is based on post-LT outcomes.