Clinical Trials

Inclusion Criteria:

• Patients 18 years old or older.
• Referred for 7T brain MRI with seizure protocol as well as normal controls.
• A subset of patients will be recruited for repeat scanning, using FDA approved T1- and T2-weighted volumetric pulse sequences, to evaluate the repeatability and validity of the results.

Exclusion Criteria: 

• Patients less than 18 years of age.
• Pregnant patients
• Patients with major brain structural lesions likely to interfere with post-processing software, including large infarcts, major congenital malformations, brain tumors and patients that have previously undergone craniotomies.
• Any patient implanted devices would be evaluated for MR safety at 7T with the standard safety protocol implemented in our 7T clinical practice.  More specifically, those individuals with safety contraindications as follows, would be excluded from research:
  • any ‘undefined’ metallic implants or foreign bodies inside the body;
  • implanted active devices such as cardiac defibrillators/pacemakers, deep brain stimulators, vagus nerve stimulators, intrathecal pumps, cochlear implants;
  • devices, or residual parts thereof left in the body such as cardiac pacer wires, which provide life assist, bone growth or pain management;
  • structural support devices, screws, or wires in bone that are near the spinal cord or temperature sensitive organs;
  • reconstructive metallic implants near the orbits;
  • external devices, medicinal patches, piercings, jewelry, clothing or hair accessories (such as wigs, weaves and extensions) within to the radiofrequency coil that cannot be removed from the body;
  • tattoos located within the radiofrequency coil;
  • permanent facial makeup;
  • metallic fragment in the eye;
  • colored contact lens;
  • fever / elevated temperature.