The TOGETHER Project - Transplant Organ Genomics to Help Prevent Rejection in Heart Transplant Recipients

Overview

About this study

The purpose of this study is to develop an RNA-seq based peripheral blood assay predictive of inflammation/rejection on allograft biopsy in adult heart transplant recipients.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Patients who meet all of the following criteria are eligible for enrollment as study participants:

Adult (≥18 years) solitary heart transplant recipient
Patient is willing and able to provide informed written consent

Exclusion Criteria:

Patients who meet any of these criteria are not eligible for enrollment as study participants:

Adult (<18 years) heart transplant recipient
Patient refusal to enroll in the study
Any simultaneous heart and extra organ transplant, including pancreas, liver, lung, kidney, etc. Subjects who have had previous transplants may be included.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Naveen Pereira, M.D.	Closed for enrollment	Contact information: Leah Majerus B.S. Majerus.Leah@mayo.edu
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator D Steidley, M.D.	Closed for enrollment	Contact information: Angela Eyshou M.B.A. (480) 342-6536 Eyshou.Angela@mayo.edu
Jacksonville, Fla. Mayo Clinic principal investigator Daniel Yip, M.D.	Closed for enrollment	Contact information: Joel Espinoza B.S. Espinoza.Joel@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Naveen Pereira, M.D.

Closed for enrollment

Contact information:

Leah Majerus B.S.

Majerus.Leah@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

D Steidley, M.D.

Closed for enrollment

Contact information:

Angela Eyshou M.B.A.

(480) 342-6536

Eyshou.Angela@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Daniel Yip, M.D.

Closed for enrollment

Contact information:

Joel Espinoza B.S.

Espinoza.Joel@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials