Pulmonary Rehabilitation in End-Stage Liver Disease

Overview

About this study

The purpose of this study is to assess the impact of exercise on sarcopenia and frailty. The exercise that will be performed in this study will include either pulmonary rehabilitation or a formal home based video strengthening program

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Wait listed for liver transplantation with poor 6 MWT

Exclusion Criteria:

Age < 18 years
Recent hospitalization (within 14 days) due to decompensation, variceal bleeding in the previous 1 month
Large esophageal varices without primary prophylaxis
Active excessive alcohol intake (in the previous 3 months)
Current overt uncontrolled hepatic encephalopathy
Hepatopulmonary syndrome with uncontrolled hypoxia
Portopulmonary hypertension
Inability to perform exercise
Marked symptomatic comorbidities (cardiac, pulmonary, renal)

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Kymberly Watt, M.D.	Closed for enrollment	Contact information: Elizabeth Carey M.D. (480)324-2000 Carey.Elizabeth@mayo.edu
Rochester, Minn. Mayo Clinic principal investigator Kymberly Watt, M.D.	Open for enrollment	Contact information: Kymberly Watt M.D. (507)266-1686 Watt.Kymberly@mayo.edu

Mayo Clinic Location

Status

Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Kymberly Watt, M.D.

Closed for enrollment

Contact information:

Elizabeth Carey M.D.

(480)324-2000

Carey.Elizabeth@mayo.edu

Rochester, Minn.

Mayo Clinic principal investigator

Kymberly Watt, M.D.

Open for enrollment

Contact information:

Kymberly Watt M.D.

(507)266-1686

Watt.Kymberly@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials