Clinical Trials

Inclusion Criteria:

• Healthy Knee Arm: Model inclusion criteria include being a male or female between 18 and 65 years of age who can wear shorts that allow visualization of their knees, are able to straighten their knees, lie in a supine position, and stand.

• Medial Knee OA Arm: Model inclusion criteria include being a male or female between 18 and 90 years of age with unilateral or bilateral knee medial compartment OA of at least radiographic K/L severity 2-4.

Exclusion Criteria:

• Healthy Knee Arm: Model exclusion criteria include having a lower extremity amputation, current or prior knee pain requiring activity modification or medical treatment, history of knee region fracture, body mass index (BMI) greater than 40 kg/m2, or history of knee surgery. Screening for exclusion criteria will be confirmed by oral history taking with the model candidate and BMI calculation based on height and weight information provided by the patient (described above) prior to assignment of subject ID numbers.

• Medial Knee OA Arm: Model exclusion criteria include having a lower extremity amputation, body mass index (BMI) greater than 40 kg/m2, inability to stand on affected leg or history of knee surgery. Screening for exclusion criteria will be confirmed by oral history taking with the model candidate and BMI calculation based on height and weight information provided by the patient (described above) prior to assignment of subject ID numbers.