Angiogram Based Fractional Flow Reserve FFRangio - A Validation Study

Overview

About this study

In the present study we aim at validating the computation of FFRangio values from the angiogram by comparing them to measured wire-based FFR values, in a larger scale and in a completely blinded manner. Investigation of a wide range of users in various conditions may strengthen the reliability of the FFRAngio measurements.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Male and female above 18 years old age which undergo FFR as part of their standard care
TIMI Grade Flow is equal to 3
LVEF larger than 45%.
Subjects with multi-vessel coronary artery disease, with NSTEMI are allowed.

Exclusion Criteria:

Contraindicated for FFR examination or adenosine administration
STEMI
CTO
TIMI Grade Flow below 3
Arteries supplying akinetic or severe hypokinetic territories
Prior CABG on the study vessel
Left Main stenosis, In-stent restenosis and Collaterals
Diffused atherosclerosis diseases and tandem lesions
Aorto-ostial lesion

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Joerg Herrmann, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Joerg Herrmann, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials