A Study of Application of Clonal Analysis to Study Flow Sorted Clinical Samples from Patients with Advanced Solid Tumors

Overview

About this study

This study is being done so researchers can study the genetics of your tumor to better understand how the tumor grows and spreads and collect a blood sample to analyze the genetic material (DNA).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Suspected or cytological/histologically confirmed advanced solid tumors undergoing standard of care image guided biopsy or surgical procedure
Age > 18 years
Willingness to provide tissue, blood samples for genomic analyses
International Normalized Ration (INR) < 1.5 x ULN (within 14 days prior to registration)
PTT < 1.5 x ULN (within 14 days prior to registration)
Eastern Cooperative Group (ECOG) performance status (PS) of 0-2 (Appendix I)
Platelet count >100,000 /μL (within 14 days prior to registration)
Ability to provide informed consent
Patients who have frozen tumor tissue/germline DNA available and who agreed to allow for their tissue to be utilized for other studies/shared with other institutions at the time of consent (including IRB#2130-00, P.I.: Barbara Pockaj, M.D.).

Exclusion Criteria:

In the opinion of the investigator, unfit or unsuitable to undergo standard of care image guided biopsy procedure
Women of childbearing potential MUST NOT be pregnant or breast feeding.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Mitesh Borad, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Mitesh Borad, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials