A Study to Improve Treatment of Clostridium Difficile Infection and using Information Technology to Improve the Care of Patients with Severe Clostridium Difficile Infection

Overview

About this study

The purpose of the study is to ascertain the efficacy of implementation of standard treatment guidelines for the treatment of C. difficile infection based on disease severity and number of instances of this infection.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

The criteria to diagnose “definite” cases of CDI in patients with appropriate clinical presentation of diarrhea (> 3 loose stools / day) or unexplained abdominal pain and leucocytosis, and any one of the following:

Clostridium difficile positive by polymerase chain reaction in stool in a patient with diarrhea
Endoscopic finding of pseudomembranous colitis
Endoscopic or surgical biopsies showing pseudomembranous colitis without another cause

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Darrell Pardi, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Darrell Pardi, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials