A Study to Examine Short Segmental Electrical Stimulation "inching" of the Ulnar Sensory Nerve in Detecting Mild Ulnar Neuropathies at the Elbow

Overview

About this study

This study specifically aims to examine whether a technique of ulnar sensory “inching” nerve conduction study may be useful in localizing the site of compression in mild ulnar neuropathies, where standard conduction studies are unable to precisely localize the lesion.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Clinical history compatible with ulnar neuropathy, including numbness in the medial hand and/or 4th and 5th digit
  2. No history of other upper extremity mononeuropathy (e.g. carpal tunnel syndrome) or cervical radiculopathy
  3. No history of surgery involving the ulnar nerve (e.g. nerve transposition)
  4. Normal ulnar motor and sensory amplitude at distal sites of stimulation(distal ulnar motor amplitude >6.0 mV, distal ulnar sensory (antidromic technique) amplitude > 10 uV)
  5. Age > 18 years

Exclusion Criteria:

  1. Prior history of CTS, brachial plexopathy, or C8-T1 cervical radiculopathy
  2. Findings of other neuromuscular process on EMG (median neuropathy, brachial plexopathy, C8-T1 radiculopathy, etc.)
  3. Previous ulnar nerve surgery
  4. Low ulnar motor or sensory amplitudes at distal site of stimulation
  5. Bilateral symptoms of ulnar neuropathy

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Jacksonville, Fla.

Mayo Clinic principal investigator

Devon Rubin, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available
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CLS-20313720

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