Understanding Pulmonary Fibrosis using iPSC Technology

Overview

About this study

The purpose of this study is to obtain lung fibroblasts (a cell type that participates in fibrosis of the lung) to study then in the laboratory to identify why they are different from fibroblast from normal individuals.

Once these cells are obtained, they will be grown in culture plates in the laboratory to be developed into many different cell types. These cells will be evaluated for their function in the laboratory, and to determine if they can continue to grow/function. Any cells that are left will be frozen for use in future experiments.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Subject population: Individuals of 18 years of age and older undergoing open lung biopsy for evaluation of interstitial lung disease.

Inclusion Criteria:

Individuals of 18 years of age and older undergoing open lung biopsy for evaluation of interstitial lung disease.

Exclusion Criteria:
Lack of research authorization on file

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Eva Carmona Porquera, M.D., Ph.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Eva Carmona Porquera, M.D., Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials