A Study to See if Ultrasound Shear Wave Elastography Can Find Early Heart Muscle Damage from Chemotherapy in Cancer Patients

Overview

About this study

The purpose of this study is see if a new ultrasound-based technique similar to standard clinical echocardiography, called Shear Wave Elastography, can provide reliable early detection of heart muscle damage caused by chemotherapy.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Equal numbers of three study groups
- Pediatric cancer patients < 21 years at the date of the first chemotherapy treatment
- Healthy controls < 21 years
- Adult cancer patients >21 years

Exclusion Criteria:

History of congenital heart disease
Chronic systemic illness requiring ongoing medical treatment
Trisomy 21
Anemia (hematocrit < 28%)

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator James Greenleaf, Ph.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

James Greenleaf, Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials