Clinical Trials

Inclusion Criteria - Online Patient Enrollment:

• Patients with existing clinical diagnosis of Familial Hypercholesterolemia (FH).
• Patients with genetic mutation of FH.
• Patients with an initial (pretreatment) LDL level > 190 mg/dL or total cholesterol > 300 mg/dL.
• Patients currently taking a lipid-lowering medication and have an LDL > 124 mg/dL or total cholesterol > 195 mg/dL.

Inclusion Criteria - Clinic Patient Enrollment:

• Patients with existing clinical diagnosis of FH using one of the three clinical diagnostic (US MedPed Program Criteria:
  • Simon Broome Register Criteria with diagnosis of "Probable";
  • Dutch Lipid Clinic Network Diagnostic Criteria with diagnosis of "Probable") tools for FH; or
  • Patients with genetic mutation of FH.

Exclusion Criteria:

• Have a known medical condition other than FH that is thought to contribute to hyperlipidemia (i.e., untreated hypothyroidism, nephrotic syndrome, cholestasis hypopituitarism).