A Study to Collect and Compare Biological Specimens from Patients Receiving Iodine Contrast, to Find Markers Associated with Allergic Response

Overview

About this study

The purpose of this study is to collect blood and urine specimens from patients receiving iodine contrast for a CT scan, and compare the biological markers in those from patients who have an allergic reaction versus the ones from patients who do not have an allergic reaction.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

Adult patients >18 yo
Scheduled to undergo any elective contrast-enhanced CT imaging at Mayo
Four groups of patients will be identified
- Contrast-naïve patients with no record of receiving iodinated contrast material
- Patients previously exposed to contrast material with no prior evidence of allergic or pseudoallergic reaction
- Patients previously exposed to contrast material with evidence of allergic or pseudoallergic reaction following this past exposure
- Patients with evidence of allergic or pseudoallergic reaction following their current CT exam

Exclusion Criteria

Is scheduled to receive additional iodinated contrast material from a separate contrast-enhanced exam or procedure in the 7 days prior to the CT scan in question
Is taking antihistamine or steroids at the time of CT scan
Is unable to provide blood and urine samples
Is pregnant at the time of CT scan
Is unable to provide consent
Does not receive contrast during CT exam

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Jennifer McDonald, Ph.D.	Closed for enrollment	Contact information: Cindy Fitting CCRP (507)538-3928 Fitting.Cindy@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jennifer McDonald, Ph.D.

Closed for enrollment

Contact information:

Cindy Fitting CCRP

(507)538-3928

Fitting.Cindy@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials