A Study of Mechanisms of Altered Ventilatory Control in Heart Failure

Overview

About this study

This study is being done because the investigators are trying to understand how feedback from the muscles can influence your blood pressure and breathing during exercise, and if the investigators can reduce this response in heart failure patients. The investigators are also trying to determine ways to improve tolerance to exercise in heart failure patients.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria Heart Failure Patients:

History of Heart Failure with preserved ejection fraction or with reduced ejection fraction
No history of dangerous arrhythmias
Body Mass Index less than or equal to 35 kg/m
Current non-smokers with less than 15 pack year history
Non-pregnant women
Individuals who are able to exercise without orthopedic limitations
All patients will be managed by their primary care physician or cardiologist prior to enrollment to ensure inclusion and exclusion criteria have been satisfied and participation in exercise testing is safe.

Inclusion Criteria Control Participants:

Will be matched for age, gender, height and weight and will have no history of cardiovascular related abnormalities.
Body Mass Index less than 35 kg/m
Current non-smokers with less than 15 pack year history
Non-pregnant women
Individuals who are able to exercise without orthopedic limitations

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Thomas Olson, Ph.D., M.S.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Thomas Olson, Ph.D., M.S.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials