Efficacy of PET/MRI in Detecting Metastatic Disease in Endometrial Cancer

Overview

About this study

The purpose of this study is to evaluate the ability of PET/MRI (Positron Emission Tomography/Magnetic Resonance Imaging) to give physicians preoperative information about specific sites in the body that the endometrial cancer may be present. If the PET/MRI is accurate and successful in providing this information, then women in the future may be able to have less extensive surgery for their endometrial cancer after evaluation with PET/MRI.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Biopsy-proven high-risk endometrial cancer (type 2 or grade 3 endometrioid histology)
BMI of at least 18.5 kg/m2 and less than 35 kg/m2 or axial diameter less than 25 cm
Patients who pass standard clinical MRI screening procedures
Receiving preoperative clinical evaluation at Mayo Clinic, Rochester, MN
Undergoing surgical staging and/or debulking at Mayo Clinic in Rochester, MN

Exclusion Criteria:

Allergy to FDG or gadolinium
Contraindication to MRI scanning (Extreme claustrophobia preventing PET/MRI completion, patients who are unable to lay quietly for an additional 60 minutes of imaging
Known kidney disease or poor renal function
Pregnant

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Andrea Mariani, M.D., M.S.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Andrea Mariani, M.D., M.S.

Closed for enrollment

More information

Publications

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