Neural Circulatory Control and SUDEP Risk.

Overview

About this study

The investigators believe epilepsy alters the way the body controls blood pressure, heart rate and breathing, and these changes increase the risk of sudden unexpected death in patients with epilepsy (SUDEP). SUDEP-7 is a risk scoring tool which may correlate with these changes to the heart and blood vessels. This research study measures those differences which may help identify new markers to help predict those patients at greatest risk in the future.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Adults aged 18-50
Able to consent

Exclusion Criteria:

History of non-epileptic spells/seizures,
Children/adolescents under age 18 years
Pregnancy
Non-compliance with Epilepsy Monitoring Unit safety procedures
Unable to consent
History of dysautonomia
Chronic Obstructive Pulmonary Disease (COPD)
Asthma (active requiring therapy)
Pulmonary hypertension
Known Structural Heart Disease
Heart failure
Myocardial infarction
Stroke
Seizures due to traumatic injury
Prior surgery for epilepsy
Vasculitis
Raynaud's
Smoking (current or within the last 6 months)

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Virend Somers, M.D., Ph.D.	Open for enrollment	Contact information: Choudhary Anwar Chahal M.B., Ch.B. cpl@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Virend Somers, M.D., Ph.D.

Open for enrollment

Contact information:

Choudhary Anwar Chahal M.B., Ch.B.

cpl@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials