A Study Using Spinal Stimulation During Exercise in Patients with Heart Failure

Overview

About this study

The purpose of this study is to determine if epidural spinal cord stimulation can affect blood pressure control and blood vessel resistance during exercise in heart failure patients by intercepting messages of muscle fatigue and shortness of breath.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

Heart Failure patients with reduced ejection fraction
History of ischemic or idiopathic dilated cardiomyopathy (duration > 1yr) stable for > 3mo and New York Heart Association Class I-III
Not pacemaker dependent
Body Mass Index ≤35
Ejection Fraction < 40%
Current nonsmokers with < 15 pack year history
Able to exercise

Exclusion Criteria

History of cardiopulmonary disorders and dangerous arrhythmias
Pregnant women
Taking prescribed opioid medications or have had a fusion or laminectomy at L3 or above
Have a recent drug-eluding stent
History of spinal stenosis, lumbar radiculopathy, or peripheral neuropathy
Must not currently be taking blood thinners or anticoagulant medications

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Bruce Johnson, Ph.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials