Publications

1. Singh PK, Li W, Bedwell GJ, Fadel HJ, Poeschla EM, Engelman AN. Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors. Viruses. 2022 Aug 26; 14 (9)
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2. Ballandras-Colas A, Chivukula V, Gruszka DT, Shan Z, Singh PK, Pye VE, McLean RK, Bedwell GJ, Li W, Nans A, Cook NJ, Fadel HJ, Poeschla EM, Griffiths DJ, Vargas J, Taylor IA, Lyumkis D, Yardimci H, Engelman AN, Cherepanov P. Multivalent interactions essential for lentiviral integrase function. Nat Commun. 2022 May 3; 13 (1):2416 Epub 2022 May 03
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3. O'Horo JC, Cerhan JR, Cahn EJ, Bauer PR, Temesgen Z, Ebbert J, Abril A, Abu Saleh OM, Assi M, Berbari EF, Bierle DM, Bosch W, Burger CD, Cano Cevallos EJ, Clements CM, Carmona Porquera EM, Castillo Almeida NE, Challener DW, Chesdachai S, Comba IY, Corsini Campioli CG, Crane SJ, Dababneh AS, Enzler MJ, Fadel HJ, Ganesh R, De Moraes AG, Go JR, Gordon JE, Gurram PR, Guru PK, Halverson EL, Harrison MF, Heaton HA, Hurt R, Kasten MJ, Lee AS, Levy ER, Libertin CR, Mallea JM, Marshall WF 3rd, Matcha G, Meehan AM, Franco PM, Morice WG 2nd, O'Brien JJ, Oeckler R, Ommen S, Oravec CP, Orenstein R, Ough NJ, Palraj R, Patel BM, Pureza VS, Pickering B, Phelan DM, Razonable RR, Rizza S, Sampathkumar P, Sanghavi DK, Sen A, Siegel JL, Singbartl K, Shah AS, Shweta F, Speicher LL, Suh G, Tabaja H Jr, Tande A, Ting HH, Tontz RC 3rd, Vaillant JJ, Vergidis P, Warsame MY, Yetmar ZA, Zomok CCD, Williams AW, Badley AD. Outcomes of COVID-19 With the Mayo Clinic Model of Care and Research. Mayo Clin Proc. 2021 Mar; 96 (3):601-618 Epub 2020 Dec 26
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4. Sehgal K, Fadel HJ, Tande AJ, Pardi DS, Khanna S. Outcomes in Patients with SARS-CoV-2 and Clostridioides difficile Coinfection. Infect Drug Resist. 2021; 14:1645-1648 Epub 2021 Apr 28
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5. Li W, Singh PK, Sowd GA, Bedwell GJ, Jang S, Achuthan V, Oleru AV, Wong D, Fadel HJ, Lee K, KewalRamani VN, Poeschla EM, Herschhorn A, Engelman AN. CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration. mBio. 2020 Sep 29; 11 (5) Epub 2020 Sept 29
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6. Godavarthy A, Kelly R, Jimah J, Beckford M, Caza T, Fernandez D, Huang N, Duarte M, Lewis J, Fadel HJ, Poeschla EM, Banki K, Perl A. Lupus-associated endogenous retroviral LTR polymorphism and epigenetic imprinting promote HRES-1/RAB4 expression and mTOR activation. JCI Insight. 2020 Jan 16; 5 (1)
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7. Achuthan V, Perreira JM, Sowd GA, Puray-Chavez M, McDougall WM, Paulucci-Holthauzen A, Wu X, Fadel HJ, Poeschla EM, Multani AS, Hughes SH, Sarafianos SG, Brass AL, Engelman AN. Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration. Cell Host Microbe. 2018 Sep 12; 24 (3):392-404.e8 Epub 2018 Aug 30
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8. Reiman JM, Das B, Sindberg GM, Urban MD, Hammerlund MEM, Lee HB, Spring KM, Lyman-Gingerich J, Generous AR, Koep TH, Ewing K, Lilja P, Enders FT, Ekker SC, Huskins WC, Fadel HJ, Pierret C. Humidity as a non-pharmaceutical intervention for influenza A. PLoS One. 2018; 13 (9):e0204337 Epub 2018 Sept 25
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9. Kelm DJ, White DB, Fadel HJ, Ryu JH, Maldonado F, Baqir M. Pulmonary manifestations of Q fever: analysis of 38 patients. J Thorac Dis. 2017 Oct; 9 (10):3973-3978
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10. DeSimone DC, Heaton PR, Neff BA, Dao LN, Wengenack NL, Fadel HJ. A rare case of chronic otitis externa due to Mycobacterium tuberculosis. J Clin Tuberc Other Mycobact Dis. 2017 Aug; 8:13-15 Epub 2017 May 16
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11. Dalvin LA, Thom SB, Garcia JJ, Fadel HJ, Baratz KH. Scleritis Due to Histoplasmosis. Cornea. 2016 Mar; 35: (3)402-4.
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12. Sowd GA, Serrao E, Wang H, Wang W, Fadel HJ, Poeschla EM, Engelman AN. A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin. Proc Natl Acad Sci U S A. 2016 Feb 23; 113 (8):E1054-63 Epub 2016 Feb 08
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13. Singh PK, Plumb MR, Ferris AL, Iben JR, Wu X, Fadel HJ, Luke BT, Esnault C, Poeschla EM, Hughes SH, Kvaratskhelia M, Levin HL. LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes. Genes Dev. 2015 Nov 1; 29 (21):2287-97
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14. Weaver EA, Camacho ZT, Hillestad ML, Crosby CM, Turner MA, Guenzel AJ, Fadel HJ, Mercier GT, Barry MA. Mucosal vaccination by adenoviruses displaying reovirus sigma 1. Virology. 2015 Aug; 482:60-6 Epub 2015 Mar 30
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15. Slaughter A, Jurado KA, Deng N, Feng L, Kessl JJ, Shkriabai N, Larue RC, Fadel HJ, Patel PA, Jena N, Fuchs JR, Poeschla E, Levy RM, Engelman A, Kvaratskhelia M. The mechanism of H171T resistance reveals the importance of Ndelta-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase. Retrovirology. 2014 Nov 25; 11:100
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16. Fadel HJ, Morrison JH, Saenz DT, Fuchs JR, Kvaratskhelia M, Ekker SC, Poeschla EM. TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism. J Virol. 2014 Sep 1; 88 (17):9704-17 Epub 2014 June 18
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17. Sharma A, Slaughter A, Jena N, Feng L, Kessl JJ, Fadel HJ, Malani N, Male F, Wu L, Poeschla E, Bushman FD, Fuchs JR, Kvaratskhelia M. A new class of multimerization selective inhibitors of HIV-1 integrase. PLoS Pathog. 2014 May; 10 (5):e1004171 Epub 2014 May 29
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18. Morrison JH, Guevara RB, Marcano AC, Saenz DT, Fadel HJ, Rogstad DK, Poeschla EM. Feline immunodeficiency virus envelope glycoproteins antagonize tetherin through a distinctive mechanism that requires virion incorporation. J Virol. 2014 Mar; 88 (6):3255-72 Epub 2014 Jan 03
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19. Meehan AM, Saenz DT, Guevera R, Morrison JH, Peretz M, Fadel HJ, Hamada M, van Deursen J, Poeschla EM. A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection. PLoS Pathog. 2014 Feb; 10 (2):e1003969 Epub 2014 Feb 20
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20. Fadel HJ, Guevara R, Saenz D, Poeschla EM. Mustela putorius furo *ferret) cyclophilin A mRNA. GenBank.2013;
    
21. Fadel HJ. Mustela putorius furo TRIM5alpha pseudogene mRNA, exon 8 GenBank.2012;
    
22. Fadel HJ, Saenz DT, Guevara R, von Messling V, Peretz M, Poeschla EM. Productive replication and evolution of HIV-1 in ferret cells. J Virol. 2012 Feb; 86 (4):2312-22 Epub 2011 Dec 14
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23. Fadel HJ, Saenz DT, Poeschla EM. Construction and testing of orfA +/- FIV reporter viruses. Viruses. 2012 Jan; 4 (1):184-99 Epub 2012 Jan 23
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24. Patel R, Vetter EA, Harmsen WS, Schleck CD, Fadel HJ, Cockerill FR 3rd. Optimized pathogen detection with 30- compared to 20-milliliter blood culture draws. J Clin Microbiol. 2011 Dec; 49 (12):4047-51 Epub 2011 Oct 05
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25. Fadel HJ, Poeschla EM. Retroviral restriction and dependency factors in primates and carnivores. Vet Immunol Immunopathol. 2011 Oct 15; 143 (3-4):179-89 Epub 2011 June 12
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26. Fadel HJ, Patel R, Vetter EA, Baddour LM. Clinical significance of a single positive blood culture for Staphylococcus lugdunensis. Journal of clinical Microbiology.2011;49:(4)1697-1699.
    
27. Hu C, Saenz DT, Fadel HJ, Walker W, Peretz M, Poeschla EM. The HIV-1 central polypurine tract functions as a second line of defense against APOBEC3G/F. J Virol. 2010 Nov; 84 (22):11981-93 Epub 2010 Sept 15
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28. Stern MA, Hu C, Saenz DT, Fadel HJ, Sims O, Peretz M, Poeschla EM. Productive replication of Vif-chimeric HIV-1 in feline cells. J Virol. 2010 Jul; 84 (14):7378-95 Epub 2010 May 12
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29. Shah NB, Osmon DR, Fadel H, Patel R, Kohner PC, Steckelberg JM, Mabry T, Berbari EF. Laboratory and clinical characteristics of Staphylococcus lugdunensis prosthetic joint infections. J Clin Microbiol. 2010 May; 48 (5):1600-3 Epub 2010 Feb 24
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30. Fadel HJ, Tleyjeh IM, Steckelberg JM, Wilson WR, Baddour LM. Evaluation of antibiotic therapy following valve replacement for native valve endocarditis. Eur J Clin Microbiol Infect Dis. 2009 Nov; 28 (11):1395-8 Epub 2009 Aug 25
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31. Fadel H, Temesgen Z. Maraviroc. Drugs Today (Barc). 2007 Nov; 43 (11):749-58
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32. Fadel HJ, Kumar G, Beckman TJ. 58-year-old man with fever and right eye pain. Mayo Clin Proc. 2006 Sep; 81: (9)1238-40.
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33. Kumar G, Fadel HJ, Beckman TJ. 36-year-old man with productive cough and diffuse rash. Mayo Clin Proc. 2006 Jul; 81(7):945-8.
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