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The research of Prashanthi Vemuri, Ph.D., is geared toward developing imaging methodologies to quantify early brain changes using multimodality images and applying them to understand the mechanistic underpinnings of neurodegenerative disorders and cerebrovascular disease. She primarily works on MRI, amyloid PET, and tau PET scans.
A major problem with the current clinical diagnostic criteria for AD is that once patients begin to show symptoms, substantial brain damage has already occurred. From a public health perspective, developing diagnostic instruments for early diagnosis of disease-related brain changes and understanding fundamental mechanisms through which important protective factors alter aging trajectories are crucial to translate research knowledge into effective dementia prevention trials.
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