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Research in the laboratory of Peter Storz, Ph.D., focuses on the protein kinase D (PKD) family of serine/threonine kinases. Specifically, Dr. Storz's laboratory is interested in the mechanisms by which PKD is activated and how it relays signaling to regulate tumor development, tumor cell survival and tumor cell motility.
In breast cancer, Dr. Storz and his colleagues focus on the role of PKD in regulating the invasiveness and metastasis of cells. In pancreatic cancer, they focus on the role of reactive oxygen species and PKD in the regulation of events that initiate the development of this cancer.
Research on breast cancer in Dr. Storz's laboratory focuses on how PKD regulates cell motility and invasiveness and how this knowledge can be translated to develop strategies and tools for early detection and treatment of metastatic breast cancer.
The laboratory's research on pancreatic cancer focuses on how PKD contributes to the development and progression of this cancer, as well as on the development of tools for early detection and strategies for treatment.
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