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The research of Scott L. Nyberg, M.D., Ph.D., is focused on the development of a multidisciplinary bioartificial liver program to improve the treatment of patients with liver failure and support the Mayo Clinic clinical liver transplant program.
His lab is also involved with regenerative medicine of liver disease as it pertains to treating patients in liver failure with extracorporeal bioartificial livers or implantable tissue-engineered livers, or treating patients with metabolic liver disease with hepatocyte transplantation.
The bioartificial liver is an important supportive therapy to bridge patients in liver failure to liver transplantation, or to avoid liver transplantation when spontaneous recovery is possible. Similar to hemodialysis in the treatment of kidney failure, the bioartificial liver functions outside of the patient's body. However, the bioartificial liver is a "hybrid" extracorporeal device in that it contains hepatocytes, most commonly of porcine or human origin, as a biological source of liver function.
Dr. Nyberg and his team expect that their research will lead to a "humanized" bioartificial liver device for clinical treatment of patients with liver failure.
Infórmate sobre los ensayos clínicos que abordan preguntas científicas específicas sobre la salud humana y las enfermedades.
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Ver las conclusiones revisadas por colegas que publiqué como resultado de mi investigación.