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Gina L. Mazza, Ph.D., strives to improve the design, conduct and analysis of cancer clinical trials through her collaborations and research. Her research focuses on the development and advancement of methods for addressing missing data and evaluating patient-reported outcomes. By promoting the use of optimal methods for addressing missing data, Dr. Mazza ensures more valid and efficient testing of the safety and effectiveness of new treatments. Her research also advances the ability to incorporate the patient's voice in the testing process.
The improvement of patient care inspires Dr. Mazza's research. By advancing the scientific rigor of cancer clinical trials, Dr. Mazza supports safer, more effective treatments and informs shared treatment decision-making between clinicians and patients. She promotes direct reporting by patients regarding their perceived health; presence, frequency or severity of symptoms; health-related quality of life; and treatment satisfaction. Relative to clinician reports, patient reports demonstrate greater sensitivity to changes in daily functioning or symptom burden, thus allowing for improvements in safety monitoring, symptom management and even survival. Furthermore, properly accounting for missing data supports more accurate and generalizable causal inferences regarding the safety and effectiveness of treatments in cancer clinical trials.
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Ver las conclusiones revisadas por colegas que publiqué como resultado de mi investigación.