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The laboratory of Gloria B. Kim, Ph.D., works on cell-based immunotherapies and immunoengineering technologies using engineered immune cells and biomaterials. Cellular immunotherapy holds great promise to provide novel treatment options for a wide range of diseases from cancers to autoimmune diseases. Genetic reprogramming of patient immune cells has emerged as one of the most promising treatments for hematological malignancies. This is highlighted by several chimeric antigen receptor (CAR)-T cell therapies that are Food and Drug Administration approved.
Now this field of study is moving toward developing therapies against solid tumors and other disorders. Dr. Kim's mission is to leverage her expertise in immunology, material science and biomedical engineering. She aims to develop next-generation cellular immunotherapies and immunoengineering approaches to help patients fight off immune-related diseases such as cancers, infectious diseases, autoimmune diseases and tissue damage.
Cellular immunotherapy has emerged as another pillar in oncology treatment. Dr. Kim and colleagues believe their biomedical research on cellular immunotherapies and immunoengineering, which has a great potential to be translated into the clinic, will have a direct impact on the well-being of patients. Dr. Kim's lab seeks to understand how immune cells work in health and disease. Advancing biomedical technologies that can boost the efficacy and persistence of cellular immunotherapies will further enhance the patient care at Mayo Clinic.
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