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Alexandre Gaspar Maia, Ph.D., is the head of the Functional Epigenomics Laboratory at Mayo Clinic, where he combines some of the most advanced sequencing techniques to profile the epigenomic landscape at a single-cell level. Dr. Maia primarily focuses on enhancer elements and transcriptional dependencies in ovarian cancer.
Dr. Maia has done extensive work in epigenetic regulation of stem cells, cellular reprogramming and cancer. He is interested in using epigenomic profiling of enhancer elements to decipher cellular heterogeneity, particularly to understand cancer stem cell states.
Advancing the current understanding of cancer stem cell states is extremely valuable for designing novel therapies and target transcriptional dependencies for each patient. This is ultimately the goal of personalized medicine.
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