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Nilufer Ertekin-Taner, M.D., Ph.D., is a neurogeneticist focused on the complex genetics of Alzheimer's disease (AD) and other neurodegenerative diseases. She is also a practicing board-certified neurologist with subspecialty training in behavioral neurology.
Dr. Ertekin-Taner's laboratory aims to discover and characterize the genetic factors that influence the risk of AD and other neurodegenerative diseases, such as progressive supranuclear palsy (PSP), through the use of combined genomic, transcriptomic and epigenetic approaches. Further, her laboratory utilizes biological traits such as cognition to study the downstream effects of genetic factors. Identification of genetic risk factors for AD in African-Americans and atypical forms of AD are additional ongoing projects in the laboratory.
The overall focus areas in Dr. Ertekin-Taner's laboratory fall in two main categories: genetics of gene expression in AD and PSP, and mapping and functional characterization of AD risk factors. Some of the ongoing projects in these areas are as follows:
Dr. Ertekin-Taner's ultimate research goal is to shed light on the details of the underlying pathophysiology of Alzheimer's and other neurodegenerative diseases, and to potentially provide therapeutic targets. Her studies on the genetics of AD are likely to lead to a better understanding of the disease and may reveal novel pathways that influence this common, complex disease.
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