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With focuses on fundamental discovery and translational efforts, the laboratory of Atta Behfar, M.D., Ph.D., has established several technologies that have yielded clinical trials in the regenerative medicine space. Within Mayo Clinic's Van Cleve Cardiac Regenerative Medicine Program https://www.mayo.edu/research/centers-programs/van-cleve-cardiac-regenerative-medicine-program/overview, Dr. Behfar and his colleagues are doing research to develop novel diagnostic and therapeutic tools to prevent and cure chronic heart conditions. Through these efforts, the program has established multiple stem cell- and exosome-based therapies extending well beyond the heart to encompass collaborative research in orthopedics, wound healing, pulmonary medicine and neurodegeneration.
Cardiovascular regeneration work done at Mayo Clinic offers new hope to patients with chronic heart conditions. In these patients, the current standards of care can only make their conditions less severe. These standards don't treat underlying issues. With a track record of translating regenerative therapies from research into clinical application, Dr. Behfar and his colleagues aim to develop technologies that can repair heart tissue, making quality of life much better for patients with heart disease.
Using the know-how established in regenerative medicine, Dr. Behfar and his team are pursuing new avenues to make more hearts available for transplantation. Building on existing efforts in ambulatory mechanical support, Dr. Behfar's team aims to establish new ways to increase the availability and quality of hearts donated after circulatory death and after brain death.
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