Radhika Dhamija, M.B.B.S., M.D.

Closed for Enrollment

• Research for Individualized Therapeutics in Rare Genetic Disease Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.

  The purpose of this study is to identify patients with rare genetic disorders that may potentially benefit from an ASO therapeutic based on the characteristics of their genetic disease and the causative genetic alterations and seek the research and development opportunities to have them developed, to have the safety and toxicity studies performed with the ultimate goal of treating the individual in a future N of 1 clinical trial.

• Whole Exome Sequencing for Diagnostic Odyssey Cases Evaluated at the Individualized Medicine Clinic Rochester, Minn., Scottsdale/Phoenix, Ariz.

  The purpose of this study is to test a new set of technologies called Next Generation Sequencing (NGS) that may help identify possible genetic reasons for your medical condition. NGS is a procedure that looks at all of your genes (the genetic material you have inherited from your parents) in different ways. Right now, clinical NGS is only done in outside clinical labs. In this study, Mayo Clinic is developing procedures to perform and interpret NGS in its own clinical labs. We also want to store samples and genetic information for future research.