Ensayos clínicos

This study is designed to determine if exercise echocardiography will identify ventricular and vascular function abnormalities in patients with COA that are not apparent at rest, and that exercise-induced ventricular and vascular dysfunction will predict clinical outcomes. 

The purpose of this study is to test the safety and effectiveness of Covered CP Stents to repair or prevent aortic wall injury associated with Coarctation of the Aorta (CoA). Coarctation of the aorta (CoA) is a congenital abnormality producing obstruction to blood flow through the aorta. Coarctation can occur in isolation, in association with bicuspid aortic valve or with major cardiac malformations. CoA accounts for 5-8% of the 8/1000 (4-6/10,000) children born with congenital heart disease. Most CoA is newly diagnosed in childhood; < 25% recognized beyond 10 yrs. CoA is mostly repaired in childhood by surgery or by ...

The purporse of this study is to determine if biomarker assay obtained at baseline can predict future risk of cardiovascular adverse events, and to  determine if temporal changes in biomarker levels can provide a better risk prediction compared to biomarker assay obtained at baseline.

The purpose of this study is to compare the difference in the ability to detect blood flow abnormalities between invasive assessments performed at rest versus exercise.