Primary biliary cholangitis

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Doctors who treat this condition

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Displaying 1-10 out of 16 doctors available

  1. Michele Barnhill, M.D.

    Michele Barnhill, M.D.

    1. Transplant Hepatologist
    2. Gastroenterologist
    1. Phoenix, AZ
    Areas of focus:

    Colonoscopy, Variceal band ligation, Esophagoscopy, Primary biliary cholangitis, Cirrhosis, Portal hypertension, Nonalc...oholic fatty liver disease, Primary sclerosing cholangitis, Hemochromatosis, Autoimmune hepatitis

  2. Elizabeth J. Carey, M.D.

    Elizabeth J. Carey, M.D.

    1. Internist
    2. Transplant Hepatologist
    3. Gastroenterologist
    1. Phoenix, AZ
    Areas of focus:

    Liver transplant, Primary biliary cholangitis, Primary sclerosing cholangitis, Autoimmune hepatitis

  3. Denise M. Harnois, D.O.

    Denise M. Harnois, D.O.

    1. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Pre-transplant evaluation, Liver transplant, Post-transplant long-term care, Liver problems, Hepatopulmonary syndrome, ...Primary biliary cholangitis, Cirrhosis, Liver cancer, Hepatocellular carcinoma, Cholangiocarcinoma, Alcoholic hepatitis, Nonalcoholic fatty liver disease, Primary sclerosing cholangitis

  4. Sumera I. Ilyas, M.B.B.S.

    Sumera I. Ilyas, M.B.B.S.

    1. Transplant Hepatologist
    1. Rochester, MN
    Areas of focus:

    Primary biliary cholangitis, Cirrhosis, Stage 4 colorectal cancer, Hepatocellular carcinoma, Cholangiocarcinoma, Hepati...tis C, Neuroendocrine tumor, Chronic liver disease, Nonalcoholic fatty liver disease, Primary sclerosing cholangitis, Hepatitis B, Hemochromatosis, Autoimmune hepatitis, Intrahepatic cholangiocarcinoma, Perihilar cholangiocarcinoma, Liver adenomatosis, Liver hemangioendothelioma

  5. Channa R. Jayasekera, M.D.

    Channa R. Jayasekera, M.D.

    1. Transplant Hepatologist
    2. Gastroenterologist
    1. Phoenix, AZ
    Areas of focus:

    Liver transplant, Liver problems, Primary biliary cholangitis, Jaundice, Cirrhosis, Liver cancer, Hepatocellular carcin...oma, Liver tumor, Hepatitis C, Liver injury, Portal hypertension, Alcoholic liver disease, Primary sclerosing cholangitis, Metabolic liver disease, Hepatitis B, Hemochromatosis, Liver mass

  6. Andrew P. Keaveny, M.D.

    Andrew P. Keaveny, M.D.

    1. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Pre-transplant evaluation, Liver transplant, Living donor liver transplant, Post-transplant long-term care, Liver probl...ems, Hepatopulmonary syndrome, Primary biliary cholangitis, Cirrhosis, Liver cancer, Hepatocellular carcinoma, Cholangiocarcinoma, Alcoholic hepatitis, Portal hypertension, Nonalcoholic fatty liver disease, Acute liver failure, Primary sclerosing cholangitis

  7. Konstantinos N. Lazaridis, M.D.

    Konstantinos N. Lazaridis, M.D.

    1. Gastroenterologist
    1. Rochester, MN
    Areas of focus:

    Primary biliary cholangitis, Liver cancer, Primary sclerosing cholangitis

  8. Michael D. Leise, M.D.

    Michael D. Leise, M.D.

    1. Transplant Hepatologist
    1. Rochester, MN
    Areas of focus:

    Upper endoscopy, Colonoscopy, Liver problems, Esophageal varices, Hepatopulmonary syndrome, Primary biliary cholangitis..., Hereditary hemorrhagic telangiectasia, Wilson's disease, Cirrhosis, Hepatocellular carcinoma, Cholangiocarcinoma, Hepatitis C, Alcoholic hepatitis, Portal hypertension, Nonalcoholic fatty liver disease, Primary sclerosing cholangitis, Hepatic encephalopathy, Hepatitis B, Hemochromatosis, Autoimmune hepatitis, Portopulmonary hypertension

  9. Nicole M. Loo, M.D.

    Nicole M. Loo, M.D.

    1. Internist
    2. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Pre-transplant evaluation, Liver transplant, Post-transplant long-term care, Liver problems, Hepatopulmonary syndrome, ...Primary biliary cholangitis, Cirrhosis, Liver cancer, Hepatocellular carcinoma, Cholangiocarcinoma, Hepatitis C, Alcoholic hepatitis, Nonalcoholic fatty liver disease, Acute liver failure, Primary sclerosing cholangitis, Fatty liver disease, Hepatitis B, Autoimmune hepatitis, Liver mass

  10. Tushar C. Patel, M.B., Ch.B.

    Tushar C. Patel, M.B., Ch.B.

    1. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Pre-transplant evaluation, Liver transplant, Post-transplant long-term care, Liver problems, Hepatopulmonary syndrome, ...Primary biliary cholangitis, Cirrhosis, Liver cancer, Hepatocellular carcinoma, Cholangiocarcinoma, Alcoholic hepatitis, Nonalcoholic fatty liver disease, Primary sclerosing cholangitis

Research

Mayo Clinic has been conducting research on primary biliary cholangitis for more than 40 years, and many treatments for the disease have been studied at Mayo Clinic. Mayo Clinic was one of the first centers to study ursodeoxycholic acid (UDCA) as a treatment option. Researchers are currently studying new medications — including applying a combination of therapies — for people with only a partial response to UDCA.

The Mayo Clinic research team has made many contributions to understanding the genetics of primary biliary cholangitis. They've helped find several gene variations that seem to make people more likely to develop the disease. Their discoveries are the first step toward developing targeted treatments and potentially curing the disease.

Also, researchers at Mayo Clinic have found that first-degree relatives — parents, siblings or children — of people with primary biliary cholangitis are more likely to have a protein in their blood that indicates the presence of the disease. Doctors call this a biomarker. The finding suggests that a simple blood test could help doctors detect the disease early in first-degree relatives so that treatment can begin before it causes irreversible liver damage.

Basic research related to primary biliary cholangitis and other liver diseases is conducted in the following Mayo Clinic laboratories:

Publications

See a list of publications about primary biliary cholangitis by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Primary biliary cholangitis care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Nov. 14, 2023
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Primary biliary cholangitis

Research: It's all about patients

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.