Print Departments and specialties Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery. Departments that treat this condition Psychiatry and Psychology Areas that research this condition Psychiatry and Psychology Research Doctors who treat this condition Edit search filters close Narrow your search By location Rochester, MN By last name Find a doctor whose last name begins with the letter A A Find a doctor whose last name begins with the letter B B There are no doctors whose last name begins with the letter C C There are no doctors whose last name begins with the letter D D There are no doctors whose last name begins with the letter E E active Find a doctor whose last name begins with the letter F F Find a doctor whose last name begins with the letter G G There are no doctors whose last name begins with the letter H H There are no doctors whose last name begins with the letter I I There are no doctors whose last name begins with the letter J J Find a doctor whose last name begins with the letter K K There are no doctors whose last name begins with the letter L L Find a doctor whose last name begins with the letter M M There are no doctors whose last name begins with the letter N N There are no doctors whose last name begins with the letter O O Find a doctor whose last name begins with the letter P P There are no doctors whose last name begins with the letter Q Q Find a doctor whose last name begins with the letter R R Find a doctor whose last name begins with the letter S S There are no doctors whose last name begins with the letter T T There are no doctors whose last name begins with the letter U U Find a doctor whose last name begins with the letter V V There are no doctors whose last name begins with the letter W W There are no doctors whose last name begins with the letter X X There are no doctors whose last name begins with the letter Y Y There are no doctors whose last name begins with the letter Z Z Reset all filters Search Tips Use quotes for phrases. Even if there are no auto-suggestions within the search field, hit "Search" anyway, as you may still get results. Displaying 1-1 out of 1 doctors available Last Name Initial: F Mark A. Frye, M.D. Psychiatrist Rochester, MN Areas of focus: Alcohol use disorder, Mood disorder, Bipolar disorder ResearchMayo Clinic conducts clinical trials to improve the diagnosis and treatment of bipolar disorder. Some areas of research include: Genetics and medication. Mayo is a leader in pharmacogenomics research, the study of how genetic factors can predict a person's response to a medication. One focus of Mayo Clinic research is connecting specific genetic profiles with responses to specific antidepressant drugs used to treat bipolar disorder. Treatment options for children and teens. Mayo Clinic psychiatrists are working with other specialists to determine the biological basis of bipolar disorder in children and to identify better, safer and more-effective treatments for children and teens. Drug treatment options. Mayo Clinic scientists conduct research to understand and identify the neuroanatomical and molecular changes in bipolar disorder. Their goal is to develop better and more-targeted drug treatment options based on variations in brain-imaging patterns, brain metabolism, and genetic and epigenetic makeup. Mayo Clinic is serving as the primary site for the established Individualized Medicine Biobank for Bipolar Disorder. This large-scale biobank of bipolar type I and II disorders is intended to serve as a resource for the bipolar research community. PublicationsSee a list of publications by Mayo Clinic doctors and researchers on bipolar disorder on PubMed, a service of the National Library of Medicine. By Mayo Clinic Staff Bipolar disorder care at Mayo Clinic Request an appointment Diagnosis & treatmentCare at Mayo Clinic Dec. 13, 2022 Print Related Bipolar disorder and alcoholism: Are they related? Bipolar disorder in children: Is it possible? Bipolar medications and weight gain Bipolar treatment: I vs. II Show more related content Associated Procedures Cognitive behavioral therapy Electroconvulsive therapy (ECT) Psychotherapy Transcranial magnetic stimulation Urinalysis Show more associated procedures News from Mayo Clinic Science Saturday: Could antidepressants cause treatment-emergent mania? Feb. 25, 2023, 12:00 p.m. CDT Products & Services A Book: Mayo Clinic Family Health Book Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Mayo Clinic in Rochester, Minnesota, has been recognized as one of the top Psychiatry hospitals in the nation for 2023-2024 by U.S. News & World Report. Learn more about this top honor Bipolar disorderSymptoms&causesDiagnosis&treatmentDoctors&departmentsCare atMayoClinic Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. CON-20257457 patient-care-and-health-information diseases-conditions Bipolar disorder