Clinical trials Below are current clinical trials.93 studies in Cardiovascular Medicine (open studies only). Filter this list of studies by location, status and more. Surgical Outcomes of Mitral Valve Repair Rochester, Minn. The purpose of this study is to learn more about early and late outcomes in patients after mitral valve repair. Cardiotoxic Effects of Chemotherapy in Patients with Sarcomas Rochester, Minn. The purpose of this study is to determine if two-dimensional speckle tracking echocardiography (2D-STE) derived-strain can detect early myocardial dysfunction and thus predict cardiotoxicity in sarcoma subjects undergoing anthracycline therapy and to compare three dimensional speckle tracking echocardiography (3D-STE) to 2D-STE in the same group of patients. Is Our Microbiome a Predictor of Cardiac Risk Rochester, Minn. The purpose of this study is to compare the fecal microbiota of patients with mild, moderate and severe Coronary Artery Disease (CAD) by collecting stool and blood samples from patients undergoing coronary angiograms. A Study to Evaluate the Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia Rochester, Minn., Scottsdale/Phoenix, Ariz. The purpose of this study is to determine the impact of pulse electromagnetic field (PEMF) therapy using the Bioboosti device (Biomobie Regenerative Medicine Company) and therapeutic protocol on cardiac ischemia in patients with coronary artery disease as quantified using an assessment of myocardial blood flow using 13N-ammonia myocardial perfusion positron emission tomography (PET) scanning to quantify blood flow during chemical induced stress. A Study of the Mayo Clinic College of Medicine Ultrasound System Rochester, Minn. The purpose of this study is is to assess the EPIQ-Affiniti and NG Compact ultrasound systems in a clinical environment and collect clinical data and feedback when compared to the site’s standard ultrasound system. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial Rochester, Minn., Jacksonville, Fla. Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will randomize patients in a 1:1 ratio to carotid stenting with embolic protection versus no stenting. Medical management will be uniform for all randomized treatment groups and will be centrally directed. International Bicuspid Aortic Valve Consortium (BAVCon) Rochester, Minn. Bicuspid aortic valve (BAV) disease is the most frequent congenital cardiac malformation, occurring in 0.5-1.2% of the US population. In young adults, it is generally a benign abnormality; but in older adults it is associated with thoracic aortic aneurysm or dissection in 20-30% of those with BAV. BAV is strongly associated with early development of aortic valve calcification or incompetence in >50% of BAV patients, and accounts for ~40% of the >30,000 aortic valve replacements (AVR) performed in the US each year. Yet, we know little of the etiology, cellular events and modifiers of progression of BAV to calcific aortic valve disease and we still do not understand the genetic cause(s) of BAV despite evidence for its high heritability. The Specific Aims of this study are: 1. To identify the genetic causes of bicuspid aortic valve disease and its associated thoracic aortic disease. 2. To identify potential pathways to predict the clinical course of BAV disease and for treating human BAV disease. To achieve these aims, we have created the International Bicuspid Aortic Valve Consortium (BAVCon), a consortium of institutions with cohorts of BAV patients and the expertise to fulfill the performance of these aims. Autologous Induced Pluripotent Stem Cells of Cardiac Lineage Delivered Into Heart Muscle for Congenital Heart Disease Rochester, Minn. The purpose of this study to test the feasibility and safety for autologous (from your own body) skin cells that are manufactured into stem cells of cardiac lineage to be delivered into the heart muscle to determine if those stem cells will strengthen the heart muscle and can be used as an additional treatment for the management of congenital heart disease. Exercise during Heart Cath in CHD Patients Rochester, Minn. The purpose of this study is to compare the difference in the ability to detect blood flow abnormalities between invasive assessments performed at rest versus exercise. Genotype-Phenotype Correlation in Cardiovascular Disease Rochester, Minn. This research study is being done to help characterize cardiovascular disease and improve diagnostic tests. OBJECTIVES To understand the pathogenesis, molecular mechanisms, and disease progression of heritable cardiovascular disease To evaluate the incidence of occult heritable cardiovascular disease in various populations. To correlate imaging and pathological phenotype with genotype to the ends described above. Pagination Clinical studies PrevPrevious Page Go to page 11 Go to page 22 Go to page 33 Go to page 44 Go to page 55 NextNext Page Request an appointment Expertise & rankingsResearch March 16, 2024 Share on: FacebookTwitter Mayo Clinic in Rochester, Minnesota, has been recognized as one of the top Cardiology & Heart Surgery hospitals in the nation for 2023-2024 by U.S. News & World Report. Learn more about this top honor Cardiovascular MedicineDepartmenthomeSectionsOverviewRequest an appointmentTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an appointmentOverviewTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20121929 departments-centers Cardiovascular Medicine