Clinical Trials

The purpose of this study is to determine if cells from a patient's own adipose tissue is safe and capable of helping regenerate the femoral head in patients with osteonecrosis. The standard of care is known as hip decompression which simply removes dead tissue from the femoral head and creates a new cavity to be filled in by healthy bone. This trial will use hip decompression plus saline injection in one hip and hip decompression supplemented with adipose derived regenerative cells in patients with osteonecrosis in both of their hips.

The purpose of this study is to describe the outcome and complications in surgical management of Preiser',s disease in the past 30 years in the Mayo Clinic.

The purpose of this study is to determine if the concentration of mesenchymal stem cells in the joint fluid of the hip increases to compare with the severity of the disease in patients with osteonecrosis ( bone decay) of the femoral head (leg bone/hip joint).

Legg-Calvé-Perthes disease is a childhood hip disorder which is common enough to be a significant public health problem (affects 1 in 740 boys between ages 0-14), but uncommon enough to have a sufficient number of patients from a single institution to perform a definitive prospective study comparing the results of current treatments. The present study will establish a database of prospectively identified patients with Legg-Calvé-Perthes (LCP) Disease and collect information regarding their presentation, treatment, and outcomes in the course of receiving currently available treatments. This study seeks to compare the outcomes of current treatments in the management of different ...

The purposes of this study is to isolate RNA from bone tissues from ONFH and osteoarthritis (OA) femoral heads and perform RNA sequencing to measure gene expression.

The purpose of this study is to update rates of union after medial femoral condyle bone grafting for scaphoid nonunion, determine subjective patient outcomes after this procedure, determine radiographic results after this procedure.

The purpose of this study is to compare the outcome of primary anatomic shoulder arthroplasty using the Stryker ReUnion system with implantation of either a peg or keel glenoid construction.

The purpose of this study is to evaluate safety and efficacy and show non-inferiority of the investigational PERFORM Stemless Reverse device to the control PERFORM Stem Reverse device in subjects who are candidates for the treatment of noninflammatory degenerative joint disease (i.e., osteoarthritis), avascular necrosis, pseudoparalysis or anterior superior escape, rotator cuff tear arthropathy, correction of functional deformity, and post-traumatic arthritis.