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Aortic Complications in Pregnant Women with Known Bicuspid Aortic Valve
Rochester, MN
The study aims to analyze echocardiogram data of women of reproductive age (18-45) with known bicuspid aortic valve disease and determine if pregnancy leads to increased rates of aortic dilation, surgical repair and/or dissection.
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International Bicuspid Aortic Valve Consortium (BAVCon)
Rochester, MN
Bicuspid aortic valve (BAV) disease is the most frequent congenital cardiac malformation, occurring in 0.5-1.2% of the US population. In young adults, it is generally a benign abnormality; but in older adults it is associated with thoracic aortic aneurysm or dissection in 20-30% of those with BAV. BAV is strongly associated with early development of aortic valve calcification or incompetence in >50% of BAV patients, and accounts for ~40% of the >30,000 aortic valve replacements (AVR) performed in the US each year. Yet, we know little of the etiology, cellular events and modifiers of progression of BAV to calcific aortic ...
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Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms
Rochester, MN
This is a prospective, non-randomized, single center, data collection study of patients treated with open surgical repair (OR) for complex aortic aneurysms (CAAs).
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A Study to Evaluate Aortic Dilatation in Patients with Conotruncal Abnormalities
Rochester, MN
The purpose of this study is to assess operative and postoperative outcomes after aortic valve surgery, evaluate for changes in ascending aorta diameter by comparing pre-operative CT imaging to measurements on follow-up imaging, and examine late outcomes and functional status during the follow-up period with specific focus on mortality, need for re-operation and incidence of aortic dissection.