Telomere Length and Telomerase Activity Effect on In Vitro Outcomes

Overview

About this study

The purpose of this study is to evaluate change in telomerase activity as a marker of oocyte quality by evaluating correlation with blastocyst embryo development and clinical pregnancy rate.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Women age 18-44 years of age.
  • Undergoing autologous IVF planning for monitoring at Mayo Clinic Rochester with an antagonist or long luteal protocol, planned fresh embryo transfer, conventional or ICSI insemination with ejaculate sperm.

Exclusion Criteria:  

  • Women undergoing donor oocyte, donor embryo cycles, oocyte cryopreservation cycles, planned freeze all, TESE or micro TESE sperm.
  •  Patients undergoing cycles for fertility preservation, minimal stimulation in 
    vitro fertilization, or with planned cleavage stage embryo transfer

Eligibility last updated 10/11/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Alessandra Ainsworth, M.D.

Open for enrollment

Contact information:

Alessandra Ainsworth M.D.

Ainsworth.Alessandra@mayo.edu

More information

Publications

Publications are currently not available