Inclusion Criteria:

- Age 19 or over at time of informed consent.

- Diagnosis of metastatic renal cell cancer (mRCC) with no prior systemic therapy for
mRCC.

1. Prior surgery and radiation therapy are permitted.

2. Prior neoadjuvant and adjuvant therapy for non-metastatic renal cell carcinoma
are permitted.

3. Patients currently not on therapy and being observed are permitted.

- Evidence of signed and dated informed consent document indicating that the patient has
been informed of all pertinent aspects of the study.

- Ability to comply with completion of PROs

Exclusion Criteria:

- Patients being treated for active malignancies other than mRCC are excluded, unless
all systemic therapy was completed at least 3 months prior to enrollment.

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 4/12/23. Questions regarding updates should be directed to the study team contact.