A Study to Assess Glycemic Variability and Fluctuations in Cognitive Status in Adults with Type 1 Diabetes

Overview

Información sobre este estudio

The objective for thisstudy is to characterize the impact of glycemic excursions on cognition in Type 1 Diabetes (T1D) and determine mediators and moderators of this relationship. This study will allow us to determine how glycemic excursions impact cognition, as well as to identify mediators and moderators of this relationship that could lead to novel interventions.

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria:

  • Aged ≥ 18 years of age.
  • Clinical diagnosis of insulin dependent presumed autoimmune type 1 diabetes by the site investigator.
  • Disease duration of > 1 year.
  • Fluent in English (capable of consenting to the study and following task instructions in English).
  • Participant understands the ecological momentary assessment and agrees to comply with it to the best of their ability.
  • Has 24-hour access to a smart phone with reliable internet access.

Exclusion Criteria:

  • Individuals < 18 years of age.
  • Unable to complete cognitive assessments due to significant visual, motor or hearing impairment.
  • Any medical or psychiatric condition or treatment (via clinic medical records) that is judged by the PIs to interfere with the completion of the study (e.g., active dialysis or chemotherapy, recent myocardial infarction, inpatient psychiatric admission, organ transplant, acute neurological insult, terminal medical condition).
  • Clinical diagnosis of dementia based on clinic medical record data.
  • Current use of real-time continuous glucose monitoring.
  • Unable to complete EMA assessments between 9am – 9pm through the study period (e.g., night shift work, planned travel across time zones, or occupation that does not reliably allow breaks to complete assessments within a reasonable period; e.g., within an hour).

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus Contacto

Rochester, Minn.

Investigador principal de Mayo Clinic

Yogish Kudva, M.B.B.S.

Abierto para la inscripción

Contact information:

Corey Kurek

(507) 255-0316

Reid.Corey@mayo.edu

More information

Publicaciones

Publications are currently not available