Detection of Periprosthetic Joint Infection in Synovial Fluid

Overview

Información sobre este estudio

The purpose of this study is to demonstrate the tests' performance when compared to the detection of periprosthetic joint infection (PJI) using the Musculoskeletal Infection Society (MSIS) criteria-based definition of PJI for diagnosing PJI. This criteria-based definition of PJI places emphasis on culture techniques that identify pathogens, but also provides for minor criteria that can be used to diagnose PJI. This study will also calculate the tests' clinical sensitivity, clinical specificity, positive predictive value (PPV), and negative predictive value (NPV).

Elegibilidad para la participación

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria:

  • Subject has a total knee and/or hip joint arthroplasty
  • The subject will be evaluated for revision surgery. Operative samples are required for full MSIS classification.
  • Subject is ≥22 years of age. -
  • Subject has had no recent injections or surgeries of the joint (within past 6 weeks). -
  • Subject has or will have all of the medical tests required to allow MSIS classification.
  • Subject signs informed consent form.

Exclusion Criteria:

  • Subject does not have a total knee and/or hip joint arthroplasty.
  • Healthy subjects without medical need for aspiration.
  • Subject did not have a revision surgery.
  • Subjects with a diagnostic synovial fluid specimen collection within the past 14 days.
  • Subjects <22 years of age.
  • Subject has had an injection, lavage, or surgery of the joint within the past 6 weeks.
  • Subject does not have all of the medical tests required for MSIS classification.
  • Subject does not sign informed consent form.

Sedes participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Sede de Mayo Clinic Estatus

Scottsdale/Phoenix, Ariz.

Investigador principal de Mayo Clinic

Robin Patel, M.D.

Cerrado para la inscripción

Rochester, Minn.

Investigador principal de Mayo Clinic

Robin Patel, M.D.

Cerrado para la inscripción

More information

Publicaciones

Publications are currently not available

Información adicional de contacto

Formulario de contacto para ensayos que no son sobre cáncer

Teléfono: 800-664-4542 (llamada gratis)

Preguntas de estudios clínicos para pacientes internacionales